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Question 1
What is the half-life of Dabigatran?

a) 5-13 hours

b) 12-17 hours

c) 4-6 hours

d) 12 hours

Question 2
Which of the following statements are true when comparing concentration-time profiles for Dabigatran 150 mg BD and Rivaroxaban 20 mg OD?

a) Rivaroxaban shows peaks and troughs above and below the therapeutic range

b) Peaks put patients at risk of bleeding and troughs put patients at risk of embolism

c) Dabigatran remains within the therapeutic range across 24 hours, providing protection against bleeding and embolic complications

d) All of the above

Question 3
How many BD doses can be missed to be equivalent to missing one OD dose?

a) One

b) Two

c) Three

d) Four

Question 4
When is Dabigatran 100 mg BD indicated?

a) Patients older than 80 years

b) Patients older than 75 years with previous GI bleeding

c) Patients older than 75 years with moderate renal impairment

d) All of the above