Click here to watch video Name: Surname: MP number: Email address: Contact telephone number: Which bacteria causes up to 90 % of uncomplicated urinary tract infections? a.Enterococcus faecalis b.Klebsiella spp. c.Proteus spp. d.Escherichia coli e.Staphylococcus saprophyticus Complete the sentence: Urinary tract infections (UTIs) are mainly limited to the upper layer of the ………………. and urethral mucosa. a.Bladder b.Kidney How do E. coli bacteria attach to the bladder wall? a.Proteins embedded within the bacterial cell wall binds to specific receptor molecules on bladder wall cells. b.By means of adhesive, hair-like structures called fimbriae. c.By means of long mobile appendages called flagella. d.By producing extracellular polysaccharides to stick to the bladder wall. e.None of the above. What is the name of the structure formed through interbacterial adhesion of E. coli on the bladder wall? a.Interbacterial conglomerate b.Biofilm c.Adhesin molecule d.Diffusion capsule e.Polysaccharide complex Choose the correct statement/s. a.A bacterial biofilm has a sticky, gel-like consistency. b.A biofilm protects bacteria from the immune system. c.A biofilm protects bacterial from antibiotics. d.Bacteria in biofilms can eventually develop bacterial resistance. e.All of the above. How does fosfomycin trometamol destroy the bacteria? a.It isolates the bacteria in a biofilm. b.It destroys the bacterial DNA and prevents it from replicating. c.It destroys the bacterial cell wall. d.It paralyses the bacterial flagella and prevents in from moving. e.None of the above. Select the correct statement/s. a.Fosfomycin is a bactericidal antibiotic. b.Fosfomycin inhibits the initial step in the biosynthesis of peptidoglycan. c.Fosfomycin acts as a phosphoenolpyruvate (PEP) analogue. d.Fosfomycin irreversibly inhibits the enzyme enolpyruvyl tranferase (MurA). e.All of the above. Choose the INCORRECT statement. a.Fosfomycin trometamol blocks and enzyme to interrupt bacterial cell wall synthesis. b.Fosfomycin trometamol has no effect on the adhesion of E. coli to the uroepithelium. c.Through its actions on adhesion of E. coli to the uroepithelium, fosfomycin trometamol halts the development of biofilm. d.Fosfomycin trometamol is able to destroy preformed biofilms. e.Fosfomycin trometamol reduces the opportunity for E. coli to mutate and develop resistance. What is the dose of fosfomycin trometamol for uncomplicated urinary tract infections? a.3 g single dose b.3 g twice daily for 5 days c.3 g daily for 2 days d.3 g daily for 7 days e.3 g daily for 10 days Choose the correct statement about Urizone. a.Fosfomycin trometamol belongs to the fluoroquinolone class of antibiotics. b.Fosfomycin trometamol has 1 year of clinical experience. c.Fosfomycin trometamol is available as a film-coated capsule. d.Fosfomycin trometamol 3 g 1 sachet, 1 dose, 1 time has the potential to achieve 100 % compliance. e.None of the above.
